AFLIBERCEPT Solution for Injection in Pre-filled Syringe
Aflibercept
40 mg/ml
BAYER AG
| Pack size | 1 Pre-filled Syringe |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 3028.60 AED |
Indications
AFLIBERCEPT Solution for Injection in Pre-filled Syringe is used for:
The opthalmic agent is used for the treatment of neovascular (wet) age-related mascular degeneration (AMD) and macular edema following central retinal vein occulsion (CRVO). The systemic injection, known as ziv-aflibercept, in combination with 5-fluorouracil, leucovorin, irinotecan-(FOLFIRI), is for the treatment of metastatic colorectal cancer that is resistant to or progressed following treatment with oxaliplatin.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Aflibercept :
Mechanism of Action
Ablibercept is a recombinant fusion protein that acts as a decoy receptor for the ligands, vascular endothelial growth factor-A (VEGF-A) and placental growth factor (PIGF). It prevents these ligands to binding to endothelial receptors, VEGFR-1 and VEGFR-2, to suppress neovascularization and decrease vascular permeability. This ultimately will slow vision loss or the progression of metastatic colorectal cancer.
Note
AFLIBERCEPT 40 mg/ml Solution for Injection in Pre-filled Syringe manufactured by BAYER AG. Its generic name is Aflibercept. AFLIBERCEPT is availble in Saudi Arabia.
Farmaco SA drug index information on AFLIBERCEPT Solution for Injection in Pre-filled Syringe is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.