APRELEX Inhalation Solution
Iloprost (as tormetamol)
20 mcg/ml
TABUK PHARMACEUTICAL MANUFACTURING CO
| Pack size | 30 Ampoule (1 ml) |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 71.07 AED |
Indications
APRELEX Inhalation Solution is used for:
Used for the treatment of pulmonary arterial hypertension.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Iloprost (as tormetamol) :
Mechanism of Action
Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, such as carbaprostacyclin. Iloprost binds with equal affinity to human prostacyclin (Prostanoid IP) and prostaglandin EP1 receptors. Iloprost constricts the ilium and fundus circular smooth muscle as strongly as prostaglandin E2 (PGE2) itself. Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. All of these properties help to antagonize the pathological changes that take place in the small pulmonary arteries of patients with pulmonary hypertension.
Note
APRELEX 20 mcg/ml Inhalation Solution manufactured by TABUK PHARMACEUTICAL MANUFACTURING CO. Its generic name is Iloprost (as tormetamol). APRELEX is availble in Saudi Arabia.
Farmaco SA drug index information on APRELEX Inhalation Solution is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.