BIOCAFFCIT Solution for Injection
Caffeine Citrate
10 mg/ml
Pharmaceutical Solution Industries Ltd.
| Pack size | 10 Vial (2 ml) |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 79.79 AED |
Available as:
Indications
BIOCAFFCIT Solution for Injection is used for:
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Caffeine Citrate :
Mechanism of Action
Caffeine stimulates medullary, vagal, vasomotor, and respiratory centers, promoting bradycardia, vasoconstriction, and increased respiratory rate. This action was previously believed to be due primarily to increased intracellular cyclic 3′,5′-adenosine monophosphate (cyclic AMP) following inhibition of phosphodiesterase, the enzyme that degrades cyclic AMP. It is now thought that xanthines such as caffeine act as antagonists at adenosine-receptors within the plasma membrane of virtually every cell. As adenosine acts as an autocoid, inhibiting the release of neurotransmitters from presynaptic sites but augmenting the actions of norepinephrine or angiotensin, antagonism of adenosine receptors promotes neurotransmitter release. This explains the stimulatory effects of caffeine. Blockade of the adenosine A1 receptor in the heart leads to the accelerated, pronounced "pounding" of the heart upon caffeine intake.
Note
BIOCAFFCIT 10 mg/ml Solution for Injection manufactured by Pharmaceutical Solution Industries Ltd.. Its generic name is Caffeine Citrate. BIOCAFFCIT is availble in Saudi Arabia.
Farmaco SA drug index information on BIOCAFFCIT Solution for Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.