ELIDEL Cream
Pimecrolimus
1%
Boehringer Ingelheim GmbH
| Pack size | 1 Tube (30 g) |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 112.35 AED |
Indications
ELIDEL Cream is used for:
For treatment of mild to moderate atopic dermatitis.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Pimecrolimus :
Mechanism of Action
Pimecrolimus binds with high affinity to macrophilin-12 (FKBP-12) and inhibits the calcium-dependent phosphatase, calcineurin. As a consequence, it inhibits T cell activation by blocking the transcription of early cytokines. In particular, pimecrolimus inhibits at nanomolar concentrations Interleukin-2 and interferon gamma (Th1-type) and Interleukin-4 and Interleukin-10 (Th2-type) cytokine synthesis in human T cells. Also, pimecrolimus prevents the release of inflammatory cytokines and mediators from mast cells in vitro after stimulation by antigen/lgE.
Note
ELIDEL 1% Cream manufactured by Boehringer Ingelheim GmbH. Its generic name is Pimecrolimus. ELIDEL is availble in Saudi Arabia.
Farmaco SA drug index information on ELIDEL Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.