FIXIT Capsule, Hard
Nizatidine
150 mg
A.H.ROBINS
| Pack size | 28's Pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 1.87 AED |
Available as:
Indications
FIXIT Capsule, Hard is used for:
Benign gastric and duodenal ulceration, Gastro-oesophageal reflux disease
Adult Dose
Oral
Benign gastric and duodenal ulceration; NSAID-associated ulceration
Adult: 300 mg at bedtime or in 2 divided doses for 4-8 wk.
Maintenance: 150 mg at bedtime.
Gastro-oesophageal reflux disease
Adult: 150-300 mg bid for up to 12 wk.
Child Dose
GERD
<12 years: 5-10 mg/kg/day PO divided q12h
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
<20 150 mg every other day. Maintenance: 150 mg every 3 days.
20-50 150 mg/day. Maintenance: 150 mg every other day.
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity.
Precautions
Possibility of malignancy should be excluded prior to therapy as the drug may mask symptoms and delay diagnosis of gastric malignancy. Increased risk of community-acquired pneumonia. Renal impairment. Pregnancy and lactation. Patient Counselling May impair ability to drive, operate machinery and perform hazardous tasks.
Lactation: crosses into breast milk, either discontinue nursing or the drug
Pregnancy-Lactation
Interactions
May increase absorption of aspirin when used in high-doses. May decrease bioavailability w/ antacids.
Adverse Effects
Side effects of Nizatidine :
>10%
Headache (17%)
1-10%
Abdominal pain, Anxiety, Constipation, Diarrhea, Dizziness, Insomnia, Nausea/vomiting, Pruritus
<1%
Anemia, Increased LFT's
Potentially Fatal: Anaphylaxis.
Mechanism of Action
Nizatidine is a histamine H2-receptor antagonist. It blocks histamine H2-receptors on gastric parietal cells resulting in decreased gastric acid secretion, gastric volume and hydrogen ion concentration.
Note
FIXIT 150 mg Capsule, Hard manufactured by A.H.ROBINS. Its generic name is Nizatidine. FIXIT is availble in Saudi Arabia.
Farmaco SA drug index information on FIXIT Capsule, Hard is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.