Galtipex Solution for Injection
Glatiramer acetate
1 ml
ASPEN HEALTHCARE MALTA LIMITED
| Pack size | 12 Pre-filled Syringe (1 ml) |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 322.02 AED |
Indications
Galtipex Solution for Injection is used for:
For reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Glatiramer acetate :
Mechanism of Action
Glatiramer acetate (GA) exhibits strong and promiscuous binding to MHC molecules (HLA DRB1* variants) and consequent competition with various myelin antigens for their presentation to T cells. A further aspect of its action is potent induction of specific suppressor cells of the T helper 2 (Th2) type that migrate to the brain and lead to in situ bystander suppression. Furthermore, the GA-specific cells in the brain express the anti-inflammatory cytokines IL-10 and transforming growth factor beta, in addition to brain-derived neurotrophic factor, whereas they do not express the inflammatory cytokine IFN-gamma. Recent evidence also suggests that Glatiramer acetate directly inhibits dendritic cells and monocytes - both of which are circulating antigen presenting cells.
Note
Galtipex 1 ml Solution for Injection manufactured by ASPEN HEALTHCARE MALTA LIMITED. Its generic name is Glatiramer acetate. Galtipex is availble in Saudi Arabia.
Farmaco SA drug index information on Galtipex Solution for Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.