Pergoveris Solution for Injection in Pre-filled Pen
Follitropin alfa, Lutropin alfa
300 IU +150 IU
MERCK SERONO S.p.A.
| Pack size | 1 Pre-filled pen (0.48 ml) |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 607.80 AED |
Indications
Pergoveris Solution for Injection in Pre-filled Pen is used for:
FOLLITROPIN ALPHA
In women having been diagnosed with primary ovarian failure, it is used in combination with human chorionic gonadotropin (hcg) to assist in ovulation and fertility. In men with hypogonadotrophic hypogonadism, it is used to induce spermatogenesis. Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (gift) or in vitro fertilization (ivf)
LUTROPIN ALFA
For treatment of infertility in women with hypothalamic or pituitary insufficiency (hypogonadotropic hypogonadism) and profound lh deficiency (lh <1. 2 international units [iu]/l)
In women having been diagnosed with primary ovarian failure, it is used in combination with human chorionic gonadotropin (hcg) to assist in ovulation and fertility. In men with hypogonadotrophic hypogonadism, it is used to induce spermatogenesis. Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (gift) or in vitro fertilization (ivf)
LUTROPIN ALFA
For treatment of infertility in women with hypothalamic or pituitary insufficiency (hypogonadotropic hypogonadism) and profound lh deficiency (lh <1. 2 international units [iu]/l)
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Follitropin alfa, Lutropin alfa :
Mechanism of Action
FOLLITROPIN ALPHA
Follitropin is important for spermatogenesis, gonadal steroid production and follicule growth and maturation
LUTROPIN ALFA
Luteinizing hormone binds to a receptor shared with the human chorionic gonadotropin hormone (hcg) on the ovarian theca (and granulosa) cells and testicular leydig cells. This lh/cg transmembrane receptor is a member of the super-family of g protein-coupled receptors. Adenylate cyclase then activates many other pathways leading to steroid hormone production and other follicle maturation processes
Follitropin is important for spermatogenesis, gonadal steroid production and follicule growth and maturation
LUTROPIN ALFA
Luteinizing hormone binds to a receptor shared with the human chorionic gonadotropin hormone (hcg) on the ovarian theca (and granulosa) cells and testicular leydig cells. This lh/cg transmembrane receptor is a member of the super-family of g protein-coupled receptors. Adenylate cyclase then activates many other pathways leading to steroid hormone production and other follicle maturation processes
Note
Pergoveris 300 IU +150 IU Solution for Injection in Pre-filled Pen manufactured by MERCK SERONO S.p.A.. Its generic name is Follitropin alfa, Lutropin alfa. Pergoveris is availble in Saudi Arabia.
Farmaco SA drug index information on Pergoveris Solution for Injection in Pre-filled Pen is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.