Sermitor Tablet

Toremifene (as citrate)
60 mg
MSN LABORATORIES PRIVATE LIMITED
Pack size 30's Pack
Dispensing mode
Source
Agent
Retail Price 5.17 AED

Indications

Sermitor Tablet is used for: For the treatment of metastatic breast cancer in postmenopausal women with estrogen receptor-positive or receptor-unknown tumors. Toremifene is currently under investigation as a preventative agent for prostate cancer in men with high-grade prostatic intraepithelial neoplasia and no evidence of prostate cancer.

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Toremifene (as citrate) :

Mechanism of Action

Toremifene is a nonsteroidal triphenylethylene derivative. Toremifene binds to estrogen receptors and may exert estrogenic, antiestrogenic, or both activities, depending upon the duration of treatment, animal species, gender, target organ, or endpoint selected. The antitumor effect of toremifene in breast cancer is believed to be mainly due to its antiestrogenic effects, in other words, its ability to compete with estrogen for binding sites in the cancer, blocking the growth-stimulating effects of estrogen in the tumor. Toremifene may also inhibit tumor growth through other mechanisms, such as induction of apoptosis, regulation of oncogene expression, and growth factors.

Note

Sermitor 60 mg Tablet manufactured by MSN LABORATORIES PRIVATE LIMITED. Its generic name is Toremifene (as citrate). Sermitor is availble in Saudi Arabia. Farmaco SA drug index information on Sermitor Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Toremifene (as citrate) :