ZAVEDOS Solution for Injection
Idarubicin hydrochloride
1 mg/ml
Zydus Hospira Oncology Private Limited ZHOPL
| Pack size | 1 Vial (5 ml) |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 183.40 AED |
Available as:
Indications
ZAVEDOS Solution for Injection is used for:
For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Idarubicin hydrochloride :
Mechanism of Action
Idarubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Idarubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.
Note
ZAVEDOS 1 mg/ml Solution for Injection manufactured by Zydus Hospira Oncology Private Limited ZHOPL. Its generic name is Idarubicin hydrochloride. ZAVEDOS is availble in Saudi Arabia.
Farmaco SA drug index information on ZAVEDOS Solution for Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.