ZEVTERA Powder for Concentrate for Solution for Infusion
Ceftobiprole
500 mg
DR. WILLMAR SCHWABE GmbH & CO. KG
| Pack size | 10 Vial (20 ml) |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 183.63 AED |
Indications
ZEVTERA Powder for Concentrate for Solution for Infusion is used for:
For the treatment of serious bacterial infections in hospitalised patients.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Ceftobiprole :
Mechanism of Action
Cephalosporins, such as ceftobiprole, are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as penicillins). Cephalosporins disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Beta-lactam antibiotics mimic this site and competitively inhibit PBP crosslinking of peptidoglycan.
Note
ZEVTERA 500 mg Powder for Concentrate for Solution for Infusion manufactured by DR. WILLMAR SCHWABE GmbH & CO. KG. Its generic name is Ceftobiprole. ZEVTERA is availble in Saudi Arabia.
Farmaco SA drug index information on ZEVTERA Powder for Concentrate for Solution for Infusion is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.