FLUDARA Film-coated Tablet
Fludarabine phosphate
10 mg
ALL AMERICAN PHARMACEUTICAL & NATURAL FOODS CORPORATION
| Pack size | 20's Pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 99.32 AED |
Indications
FLUDARA Film-coated Tablet is used for:
For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Fludarabine phosphate :
Mechanism of Action
Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite appears to act by inhibiting DNA polymerase alpha, ribonucleotide reductase and DNA primase, thus inhibiting DNA synthesis. The mechanism of action of this antimetabolite is not completely characterized and may be multi-faceted.
Note
FLUDARA 10 mg Film-coated Tablet manufactured by ALL AMERICAN PHARMACEUTICAL & NATURAL FOODS CORPORATION. Its generic name is Fludarabine phosphate. FLUDARA is availble in Saudi Arabia.
Farmaco SA drug index information on FLUDARA Film-coated Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.